11 results
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
hypothalamus → fever ... Lipopolysaccharide components ... Double-stranded RNA • Fungi ... Mannan and glucan components ... Pathophysiology #InfectiousDiseases
Causes of Acute Onset Fever - Differential Diagnosis Algorithm
Viral:
 • Rhinovirus
 • Influenza Virus
 • Parainfluenza
Causes of Acute ... Diagnosis Algorithm ... Infectious - Other: • Fungal ... Differential #Diagnosis #Algorithm ... #causes
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Staphylococci (skin), Gram-negative ... Staphylococci (skin), Gram-negative ... difficile (gut) • Fungi ... differential #diagnosis #causes ... #infectiousdiseases
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... Tropheryma whipplei, Fungi ... under BCNIE, these bacteria ... #culture #negative ... #Endocarditis #InfectiousDiseases
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
therapy - Number one cause ... of culture negative ... have a fastidious bacteria ... Fungal (Histoplasma ... Diagnosis #Management #Algorithm
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... cultures remain negative ... or fungi (grows ... but important causes ... differential #workup #infectiousdiseases
Soil Related Infections - Differential Diagnosis Framework

Mechanism Of Infection:
 • Wound
 • GI: Ingestion, MUD, Contaminated
rhizosphere include: bacteria ... arthropods Bacteria ... cause primary pulmonary ... dyspnea, possible fever ... differential #diagnosis #InfectiousDiseases
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
weeks) Can Be Caused ... burgdorferi • Virus/Bacteria ... • Rheumatic fever ... aureus • Gram-negative ... tuberculosis) • Fungi
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
• Cell wall component ... of many fungi ... Almost always negative ... Infections with certain bacteria ... post-2010 almost never
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
aureus, Coagulase-negative ... night sweats, fever ... • Persistent bacteremia ... /fevers > than 5 ... Diagnosis #cardiology #infectiousdiseases