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diagnosis infections lung cardiology endocarditis negative bcnie betadglucan brain culture galactomannan abscess aids biomarkers bloodculture cnie comparison cord disorders falsepositives
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture ... Negative Abscess - Differential ... antibiotics as a cause ... Negative #Abscess #Differential ... #Diagnosis #InfectiousDiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... of many fungi ... BAL GM does not differentiate ... decreased with: concurrent
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
(mucosa), Aspergillus ... : Aspergillus spp ... Infections #Timeline #differential ... #diagnosis #causes ... #infectiousdiseases
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... ) • Fungi: Aspergillus ... #Differential # ... Diagnosis #causes ... #infectiousdiseases
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... ) • Fungi: Aspergillus ... #Differential # ... Diagnosis #causes ... #infectiousdiseases
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
• Cell wall component ... of many fungi ... in BAL does not differentiate ... Sensitivity ↓ w/concurrent ... closely related fungi
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood ... Tropheryma whipplei, Fungi ... (Aspergillus, Candida ... #differential # ... #Endocarditis #InfectiousDiseases
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... presentations: • Pulmonary ... considered in certain cases ... Management #treatment #fungal ... #infectiousdiseases
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
Causes of Hemoptysis ... - Differential ... Diagnosis Algorithm ... Tuberculosis • Fungal ... #Causes #Pulmonary
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
Causes of Pericarditis ... - Differential ... Diagnosis Algorithm ... • Zoonoses Fungal ... Coccidioides immitis • Aspergillus
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