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diagnosis differential infections lung management abscess aspergillus treatment aids bacteremia betadglucan biomarkers chest clinical coccidioidomycosis comparison culture empyema en galactomannan
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... ) • Fungi: Aspergillus ... Blastomycosis, Coccidioides ... Differential #Diagnosis #causes ... #infectiousdiseases
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... ) • Fungi: Aspergillus ... Blastomycosis, Coccidioides ... Differential #Diagnosis #causes ... #infectiousdiseases
Differential Diagnosis for Concurrent Brain and Lung Infections • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
Diagnosis for Concurrent ... Brain and Lung ... Toxoplasmosis • Fungi ... Blastomycosis, Coccidioides ... Differential #Diagnosis #causes
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture ... antibiotics as a cause ... negative culture Brain ... Mycobacteria - Fungal ... Differential #Diagnosis #InfectiousDiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... of many fungi ... dermatophytes, Coccidioides ... decreased with: concurrent
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
Lipopolysaccharide components ... Double-stranded RNA • Fungi ... Mannan and glucan components ... Transport to brain ... Pathophysiology #InfectiousDiseases
Soil Related Infections - Differential Diagnosis Framework Mechanism Of Infection: • Wound • GI: Ingestion, MUD, Contaminated
include: bacteria, fungi ... cause primary pulmonary ... or sinus fungus ... Valley Fever") • Coccidioides ... differential #diagnosis #InfectiousDiseases
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Diagnosis: • Direct fungal ... • Sinusitis • Brain ... • Serology for Coccidioides ... ) #Mycoses #InfectiousDiseases ... #Fungal #Diagnosis
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... Prevotella • Fungal ... Cryptococcus - Coccidioides ... Lung #Abscess #pulmonary ... #differential #causes
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... presentations: • Pulmonary ... considered in certain cases ... Management #treatment #fungal ... #infectiousdiseases
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