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diagnosis management treatment activetb galactomannan latenttb tb tuberculosis aspergillus bacteremia biomarkers causes comparison differential falsepositives infections laboratory mycoses pulmonary rigors
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Abscess Pathophysiology ... Lung abscess ... Lung Abscess - Clinical ... Prevotella • Fungal
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... of many fungi ... Clav (may be + as long ... #Biomarkers #BetaDGlucan
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... Lipopolysaccharide components ... Double-stranded RNA • Fungi ... Mannan and glucan components ... #InfectiousDiseases
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
• Cell wall component ... of many fungi ... result in + as long ... closely related fungi ... blood products #BetaDGlucan
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... affecting the lungs ... infection (NTM) • Fungal ... abscess Primary ... • Progressive lung
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Aspergillosis Pathophysiology ... Sinusitis • Brain abscess ... change in the lungs ... nails, bronchi, lungs ... ) #Mycoses #InfectiousDiseases
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... affecting the lungs ... infection (NTM) • Fungal ... abscess Primary ... • Progressive lung
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... of infection: Lungs ... negative bacteria, fungi ... source (e.g., abscess
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