21 results
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... Double-stranded RNA • Fungi ... Mannan and glucan components ... Transport to brain ... #InfectiousDiseases
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen Pathophysiology ... Lipopolysaccharide components ... stranded RNA • Fungi ... Mannan and glucan components ... - Transport to brain
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Negative Abscess - Differential ... negative culture Brain ... Mycobacteria - Fungal ... Negative #Abscess #Differential ... #Diagnosis #InfectiousDiseases
AIDS-defining illnesses
 - Candidiasis of the esophagus, bronchi, trachea, or lungs [(but NOT the mouth (thrush)]
AIDS-defining illnesses ... bronchi, trachea, or lungs ... Toxoplasmosis of brain ... Illnesses #HIV #InfectiousDiseases ... Diagnosis #List #Differential
Blurry vision in a patient with HIV/AIDS
Anterior Segment:
 • Herpes zoster ophthalmicus
 • Keratitis (HSV, Staph,
patient with HIV/AIDS ... Candida, other fungi ... vision #HIVAIDS #InfectiousDiseases ... Anterior #Posterior #Differential
Pulmonary Infections in HIV-AIDS
Bacterial: 
 • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Infections in HIV-AIDS ... M.kansasii, MAC) Fungal ... > 200: Endemic fungi ... failure, COPD, Lung ... diagnosis #evaluation #differential
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... #Concurrent #Differential ... Diagnosis #causes #infectiousdiseases
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... #Concurrent #Differential ... Diagnosis #causes #infectiousdiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... of many fungi ... BAL GM does not differentiate ... Clav (may be + as long
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Abscess Pathophysiology ... Prevotella • Fungal ... Abscess Differential ... Abscess #pulmonary #differential