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diagnosis management differential galactomannan latenttb nodule tb tuberculosis abscess antibiotic aspergillus biomarkers comparison failure falsepositives laboratory lungmalignancy pulmonarynodule rheumatology sensitivity
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... admin of mold-active ... Clav (may be + as long ... #Biomarkers #BetaDGlucan
Pulmonary Nodule Evaluation is guided by nodule size & assessment of probability of malignancy. In addition is
diameter are called lung ... masses & should ... associated with lung ... The treatment of ... a diagnosis of lung
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... infection (NTM) • Fungal ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Lung Nodule - Differential Diagnosis Algorithm Nodule on > 2 Years Without a Change in Size: •
Lung Nodule - Differential ... Diagnosis Algorithm ... Infection: • Fungal ... Differential #Diagnosis #Algorithm ... #Causes #Pulmonary
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... infection (NTM) • Fungal ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... hemorrhage • Treatment ... Prevotella • Fungal ... #Abscess #pulmonary ... #differential #causes
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
• Cell wall component ... of many fungi ... concurrent admin mold-active ... result in + as long ... blood products #BetaDGlucan
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... bacteria: Viral, Fungal ... ocular), Tissue activity ... (daptomycin in lungs ... • Secondary to Treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... , INC risk PE, Pulmonary ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... muscarinic agonists • Active
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