13 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
thickening Signs ... Hepatic: PBC (primary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... ulcerations • Skin ... auricular papules Clinical
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... organ-specific signs ... symptoms (eg, skin ... Differential #diagnosis #hematology
Morphology of Primary Skin Lesions - Description Algorithm
Primary Skin Lesion - Initial lesion not altered by
Skin Lesions - ... Description Algorithm ... Primary Skin Lesion ... vs Deep Component ... #dermatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... Returning Traveler’ algorithm ... thin smear • Signs ... node biopsy • Clinical ... values supporting hematologic
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... Pathogenesis and clinical ... processes occur in the skin ... Subacute development, primarily ... Pathophysiology #Signs
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Algorithm and Differential ... investigations depending on clinical ... context and signs ... #Injury #AKI #Workup
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... failure PBC Signs ... Examination: • Skin ... cholangitis #diagnosis #workup ... #hepatology
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism
 • Low TSH, Low normal T4
Hyperthyroidism: Work-up ... of pregnancy, critical ... high T4 +/- T3 → Primary ... Hyperthyroidism → Signs ... Hyperthyroidism #algorithm
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Abnormalities in primary ... deficiency Work ... cryoglobulins • Skin ... #Causes #dermatology