18 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... bruising • Skin ... GI. uterine) Laboratory ... VonWillebrand #Disease ... #Diagnosis #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Differential Diagnosis Algorithm ... Hepatic, Portal, ... Myeloproliferative disorders (eg ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
suspicion of severe disease ... splenomegaly, abnormal ... - Sickle cell disease ... - Leg length discrepancy ... #Limping #NWB #Algorithm
Normal Thromboelastogram - Specific parameters represent the 3 phases of the cell-based model of haemostasis: initiation,
Normal Thromboelastogram ... ) #Diagnosis #Hematology ... Thromboelastogram #TEG ... #Normal #Interpretation ... #Laboratory
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... redness of the skin ... substantially, usually to TEN ... includes Kawasaki disease ... #Diagnosis #Dermatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... pathognomonic laboratory ... retinal damage) • Skin ... test (this is a skin ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
and fever) and laboratory ... 3rd Decade Skin ... with: • Minimal laboratory ... Seizures • Strokes Skin ... flares • CRP normal
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... inflammation (eg ... upper limit of normal ... Necrosis) If mild laboratory ... Diagnosis #Management #Hepatology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Capitis - Skin ... Disease: Discoid ... • Drugs: Oral ... of any comorbid disease ... Examine the entire skin
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Monoclonal Protein/M Component ... • Heavy Chain disease ... Alpha & Mu) Skin ... Cryoglobulinemic, Hypo/normo-complementemic ... Paraproteinemias #Hematology