17 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Localization #Nephron ... #Defects #Pathophysiology ... #Nephrology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... loop and distal component ... of Nephron: CHF ... KidneyDisease #nephrology ... #Effects #pathophysiology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... delivery to distal nephron ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... Diagnosis Algorithm ... - Bartter - Gitelman ... Cl⁻ with other components ... #Pathophysiology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ascending limb Gitelman ... Epithelial #Inherited #Defects ... #Kidney #Nephrology ... #Diagnosis #Differential
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Ptosis - Differential ... Neurogenic Ptosis - Neurologic ... due to the mass effect ... Syndrome #Ptosis #neurology ... #Differential #
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Non-reabsorbable anion effect ... Bartter syndrome, Gitelman ... urine #potassium #differential ... #algorithm #diagnosis ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... ratio 0.5%) Differential ... #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Bartter syndrome, Gitelman ... mineralocorticoid-like effect ... urine #Algorithm #nephrology ... #differential # ... diagnosis
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Metabolic Alkalosis: Differential ... Diagnosis ECF ... tubule diuretic effect ... furosemide-like lesion) • Gitelman ... #nephrology