1425 results
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
 -
in RBC internal contents ... Hemolytic #Anemia #hematology
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
In the proper context ... Smear #Microscopy #Hematology
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
Product Components, Contents ... BloodProduct #Components #Contents ... #Volume #Hematology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
administered in the context ... Transfusion #Thresholds #Hematology
JEHOVAHS WITNESS BLOOD PRODUCT AND TECHNIQUE CONSENT / DECLINE CHECKLIST

COMPONENTS OF HUMAN BLOOD: 
Red Blood Cells,
AND TECHNIQUE CONSENT ... #BloodProduct #Consent ... Checklist #Management #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
www.bloodjournal.org/content ... Chemotherapy #Oncology #Hematology
General Approach to Anemia - Differential Diagnosis Framework
1) Check reticulocyte count to determine if hypo/hyper-proliferative
2) Exclude
MCV & clinical context ... differential #diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
intracellular contents ... diagnosis #management #hematology
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
pathway): Thrombin converts ... diagnosis #models #hematology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
infection (IFI) in hematologic ... defined in clinical context