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diagnosis differential hematology treatment erythematosus infectiousdiseases lupus sle systemic acquired activation bcnie bloodculture cardiomyopathy cerebritis cns complexes conditions criticalcare dermatology
Endocarditis checklist Initial evaluation • Peripheral blood cultures (three sets at three different sites) • Additional culture
Endocarditis checklist ... if suspected (e.g ... block (+/- daily EKG ... of infection (e.g ... #diagnosis #management
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune disease
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
90% of IE cases Culture ... staphylococci Culture ... ↑ ESR, CRP • EKG ... #diagnosis #management ... #cardiology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Subacute bacterial endocarditis ... GI - Felty syndrome ... , Vasculitis (e.g ... fever - Bacterial endocarditis ... differential #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... (eg, systemic juvenile ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
Inherited arrhythmia syndromes ... (e.g., long QT ... syndrome, ARVC) ... 300 = NSVT EKG ... #differential #cardiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Infective Endocarditis ... antiphospholipid syndrome ... special stains (e.g ... exists Infectious Diseases ... Negative #Infective #Endocarditis
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
cardiomyopathy (e.g ... hemodynamics (e.g ... LVEF recovery (e.g ... teratogenic GDMT meds (e.g ... #cardiology #treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Malignancy (e.g ... Endocrine disorders (e.g ... • Libman-Sacks endocarditis ... Erythematosus #Diagnosis #Rheumatology
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