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diagnosis differential hematology treatment endocarditis acquired activation cardiomyopathy cerebritis cns complexes dermatology erythematosus hemeonc hemophagocytic hlh infectiousdiseases lupus lymphohistiocytosis macrophage
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
Inherited arrhythmia syndromes ... (e.g., long QT ... syndrome, ARVC) ... 300 = NSVT EKG ... #differential #cardiology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune disease
Palpitations - Differential Diagnosis Framework What? • It is an unpleasant awareness or sensation that the heart is
exam • 12-lead ECG ... tachycardia • Premature ... (e.g., aortic insufficiency ... Family history of premature ... #Palpitations #Cardiology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... (eg, systemic juvenile ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
cardiomyopathy (e.g ... hemodynamics (e.g ... LVEF recovery (e.g ... teratogenic GDMT meds (e.g ... #cardiology #treatment
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
90% of IE cases Culture ... staphylococci Culture ... ↑ ESR, CRP • EKG ... Endocarditis #diagnosis #management ... #cardiology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... antiinflammatory properties e.g ... osteoarticular and skin disease ... #Rheumatology # ... diagnosis #management
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
90% of IE cases Culture ... staphylococci Culture ... Cholesterol emboli syndrome ... ↑ ESR, CRP • EKG ... Differential #Diagnosis #cardiology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... ▪ Autoimmune diseases ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g
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