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diagnosis differential cardiology erythematosus hematology infectiousdiseases lupus sle systemic treatment acquired activation bcnie bloodculture cerebritis cns conditions criticalcare dermatology extrarticular
Endocarditis checklist Initial evaluation • Peripheral blood cultures (three sets at three different sites) • Additional culture
Endocarditis checklist ... if suspected (e.g ... block (+/- daily EKG ... of infection (e.g ... #diagnosis #management
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune disease
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Subacute bacterial endocarditis ... GI - Felty syndrome ... , Vasculitis (e.g ... fever - Bacterial endocarditis ... differential #diagnosis #rheumatology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Congenital heart disease ... 90% of IE cases Culture ... staphylococci Culture ... ↑ ESR, CRP • EKG ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... (eg, systemic juvenile ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Infective Endocarditis ... antiphospholipid syndrome ... special stains (e.g ... exists Infectious Diseases ... Negative #Infective #Endocarditis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Malignancy (e.g ... Endocrine disorders (e.g ... • Libman-Sacks endocarditis ... Erythematosus #Diagnosis #Rheumatology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Endocarditis - Overview ... 90% of IE cases Culture ... staphylococci Culture ... Cholesterol emboli syndrome ... ↑ ESR, CRP • EKG
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... antiinflammatory properties e.g ... osteoarticular and skin disease ... #Rheumatology # ... diagnosis #management
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