14 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Hemoglobinopathies (e.g ... Membrane defects (e.g
Diffuse Acute Abdominal Pain (<72 hours) - Differential Diagnostic Algorithm
Look for surgical abdomen
Upper quadrant: R/O cardiac,
Perforation • Ruptured ... • Peptic ulcer disease ... (e.g., Diabetic ... • Sickle cell anemia ... Irritable bowel syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Increased Requirement (e.g ... • Pancreatic Disease ... Myelodysplastic Syndromes ... • Liver Disease ... Algorithm #Causes #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune disease
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(eg, systemic juvenile ... • Infection (eg ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Diagnosis and Management ... Anemia (common) ... Budd Chiari syndrome ... Recombinant cytokines (e.g ... kinase inhibitors (e.g
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... and pernicious anemia ... unit activity on EMG ... of diazepam • EMG ... TPO, TTG, etc EMG
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Malignancy (e.g ... Endocrine disorders (e.g ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis #Rheumatology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
90% of IE cases Culture ... staphylococci Culture ... ↑ ESR, CRP • EKG ... Leukocytosis, anemia ... Endocarditis #diagnosis #management