11 results
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Workup Blood Work ... : - Hypokalemia ... - Fractional excretion ... Normotensive - No diuretic ... #Workup #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
stones caused by ... Prevention of blood ... #Renal #Excretion ... #Diuresis #Nephrology ... #Pharmacology #
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... suggests extra-renal ... Alkalosis: Emesis, Diuretics ... #differential # ... potassium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... Normal or low blood ... (renal potassium ... Surreptitious diuretic ... #nephrology #management
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • Trauma/Crush injury ... • K sparing diuretics ... diagnosis #causes ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
UA positive for blood ... Monitor potassium ... Loop diuretics for ... #causes #treatment ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... G-K), K-sparing diuretics ... (IV loop diuretic ... #Treatment #potassium ... #nephrology #K
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • Trauma/Crush injury ... • K sparing diuretics ... diagnosis #causes ... #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
loop or thiazide diuretics ... • Normal/low blood ... pressure: Active diuretic ... urine #Algorithm #nephrology ... diagnosis
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Chronic progressive kidney ... Potassium-sparing ... diuretics (amiloride ... #diagnosis #causes ... #nephrology