18 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... calcium for K; also binds ... nonspecifically binds ... #pharmacology #table ... #comparison #binders
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... Lower risk of hypercalcemia ... range - Lack of hypercalcemia ... #Phosphate #Binders ... #Table #Comparison
Comparison of Fever Algorithms for Infants <3 months old

AGE, INCLUSION, TESTS 
REQUIRED, "LOW RISK" CRITERIA, TREATMENT,
Comparison of Fever ... Algorithms for ... RISK" CRITERIA, TREATMENT ... #Algorithm #Comparison ... #Table #Performance
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Algorithm • IV ... • Consider K+ binder ... , asystole #hyperkalemia ... #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Muscle swelling - Fever ... • LDH ↑ • Hyperkalemia ... Treatment of underlying ... fluid/Lactated ringers ... per day until stable
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... hydration - Hyperkalemia ... treatment (no calcium ... Non calcium phos binders
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Algorithm for Management ... - Consider K+ binders ... bicarbonate - Consider binders ... #Algorithm #Management ... Acute #Chronic #treatment
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
explain symptoms • Fever ... : 33% • Treatment ... : No • Treatment ... hematology #diagnosis #comparison ... #table