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diagnosis pathophysiology hyperthyroidism acromegaly adrenal adverse antipsychotics cah causes congenital cushings deficiency differential exogenous feedbackloop firstgeneration gh glftap growthhormone hydroxylase
Acromegaly Caused by over-secretion of growth hormone (GH) from the pituitary gland. The condition is rare
(GH) from the pituitary ... #Acromegaly #Signs ... #Symptoms #Diagnosis ... #Endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... Signs / Symptoms ... #Macroadenoma #SideEffects ... #endocrinology
Exogenous Testosterone Side Effects • Mood disorder, Depression, Aggression • ↑ Erythropoiesis • Hypogonadism +/-BPH, prostate
#Testosterone #SideEffects ... adverse #diagnosis #signs ... #symptoms #steroids ... #endocrinology
Clinical Effects of Large and Small Pituitary Tumours Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
Large and Small Pituitary ... infarction/expansion (pituitary ... #Tumors #Signs ... #Symptoms #Diagnosis ... #Endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... and Symptoms • ... • Hypothalamic–Pituitary ... #Symptoms #diagnosis ... #endocrinology
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
-> Prefrontal Cortex ... Hypothalamus -> Pituitary ... Extrapyramidal Symptoms ... FirstGeneration #Mechanisms #SideEffects
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
TSH-producing pituitary ... #differential #endocrinology ... #signs #symptoms
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
• The adrenal cortex ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
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