14 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... ongoing ↑ LFTs or symptoms ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Diagnosis Algorithm ... non-essential drug/HDS treatments ... e.g. ascites), Chronic ... #Diagnosis #Algorithm ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Drug-Induced Liver Injury ... (DILI) Viral Hepatitis ... gastroenterology #management #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... > 2 • NASH, Chronic ... : > 3 • Chronic ... #algorithm #hepatology
Assessment of the Child with Chronic Asthma
Are there other allergic disorders?
 - Allergic rhinitis
 - Eczema,
the Child with Chronic ... and frequency of symptoms ... rhinitis needing treatment ... Asthma #Assessment #diagnosis ... #peds #pediatrics
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
Non-accidental Injury ... cell disease Rheumatology ... #Limping #NWB #Algorithm ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
- Differential Diagnosis ... Algorithm Normal ... Syndrome • Turner ... Panhypopituitarism Treatment ... #causes #pediatrics
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... • Treatment: ... • Evolution: Chronic ... #diagnosis #management
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
- Symptoms of ... chronic inflammation ... pattern of liver injury ... regarding need for treatment ... #Management #Hepatology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... Vector-borne (most ... form (No signs/symptoms ... 90-120 days • Pediatric ... Trypanosomiasis #Diagnosis