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Anemias - Differential and Diagnostic Clues

Ariella Coler-Reilly @AriellaStudies

#Anemias #Differential #Diagnosis #Clues #Hematology
Anemias - Differential ... Coler-Reilly @AriellaStudies ... #Anemias #Differential ... #Diagnosis #Clues ... #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... agents ex. lead, copper ... #Differential # ... Diagnosis #causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... #differential # ... diagnosis #hematology ... #anemia
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... the low levels ORDER ... and M panel Management ... DDX - Other causes ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential ... Diagnosis Neonate ... Megaloblastic anemia-rare ... #diagnosis #causes ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Increased Serum Copper ... Immunohistochemical studies (to differentiate ... #oncology #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... treatments • Copper ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology