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differential rheumatology scleroderma signs ana antibodies antinuclear chest emergencies hemeonc miliary oncologic oncology pathophysiology pattern patterns systemic systemicsclerosis testing workup
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
of Scleroderma (SSc ... thickening, distal to elbows ... (DcSSc; diffuse ... : ILD (interstitial ... #rheumatology #diagnosis
Miliary Pattern - Chest Radiology • Miliary opacities are scattered, small (1 -4 mm) nodules •
Pattern - Chest Radiology ... mm) nodules • Diffusely ... Differential Diagnosis ... #pulmonary #CXR ... #clinical #CT
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... or scleroderma (SSc ... • Nucleolar: Diffuse ... , Interstitial Pulmonary
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
Sclerosis (Scleroderma ... Crackles, Abnormal CXR ... - Finger/hand/elbow ... pathophysiology #signs #symptoms ... #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
suspected) - CT ... chest; CT abdomen ... interventional radiology ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
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