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differential scleroderma signs chest clinical emergencies hemeonc management miliary oncologic oncology pathophysiology prs renal rheumatology ssc syndromes systemic systemicsclerosis testing
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
thickening, distal to elbows ... and knees • Diffuse ... (DcSSc; diffuse ... : ILD (interstitial ... #rheumatology #diagnosis
Miliary Pattern - Chest Radiology • Miliary opacities are scattered, small (1 -4 mm) nodules •
Miliary Pattern ... - Chest Radiology ... mm) nodules • Diffusely ... #pulmonary #CXR ... #clinical #CT
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Inflammatory eye disease: scleritis ... Other tests: • CT ... or serologies + symptoms ... seen on chest CT ... • IF staining patterns
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
Sclerosis (Scleroderma ... Crackles, Abnormal CXR ... - Finger/hand/elbow ... pathophysiology #signs #symptoms ... #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
suspected) - CT ... chest; CT abdomen ... interventional radiology ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
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