943 results
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
development of cross-reactive ... antibodies and cross-reactive ... activation' by cross-reactive ... Rheumatic #Fever #Pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
-> GAS antigen cross-reacts ... RheumaticFever #pathophysiology
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
lobe is unable to cross ... Pathophysiology: ... neurology #diagnosis #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
binds to the lgE, cross-linking ... Classification #Pathophysiology
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
• Bacteria cross ... C5C9Deficiency #Complement #pathophysiology
Criss-Cross Gait on Physical Exam 

Seen in Glucose Transporter type 1 Deficiency Syndrome

#CrissCross #Criss #Cross #Gait
Criss-Cross Gait ... #CrissCross #Criss ... #Cross #Gait #PhysicalExam
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
fibrin, which is cross-linked ... models #hematology #pathophysiology
Lipiduria Pathophysiology
1) Damaged glomerular basement membrane allows plasma lipids to escape into Bowman's space and enter
Lipiduria Pathophysiology ... produces a "Maltese cross ... #Lipiduria #Pathophysiology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
infection that cross-reacts ... the underlying pathophysiology
Cross-Reactivity of Penicillins and Cephalosporins

Cross reactivity of penicillin-allergic patients to cephalosporins has more to do with
Cross-Reactivity ... Cephalosporins Cross ... Carbapenem cross-reactivity ... and there is no cross-reactivity