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hepatology differential aki criticalcare hematology hepatitis nephrology blood pharmacology reactions signs symptoms table treatment aclf activation acutekidneyinjury aflp aih alcoholic
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... Kidney Failure ... Injury (DILI) ... #diagnosis
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
liver failure ... Seizures Kidney ... lung injury, ... #liver #failure ... Signs #Symptoms #Diagnosis
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... cardiorenal syndrome) • Liver ... failure (a.k.a. ... #Kidney #Injury ... Classification #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... Liver Injury: ... Liver Injury:
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
Acute Kidney Injury ... urinalysis, labs - Management ... Diuretics if heart failure ... appropriate) #Acute ... #Kidney #Injury
Outpatient Hypertension Management Algorithm Monotherapy: • Thiazide/thiazide-like • ACE-I (non-black patients), • ARB
Outpatient Hypertension Management ... Algorithm Monotherapy ... Left Ventricular Failure ... Kidney Injury ... #Algorithm #PrimaryCare
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Failure ( ... cardiac muscle, RBC, Kidney ... Cardiac muscle, Kidneys ... trimester placenta, kidneys ... #chemistry #diagnosis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... acid metabolism products ... headache, malaise) → Acute ... liver failure rapidly ... → Multiorgan failure
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... Skin involvement, Kidney ... dechallenge • Acute ... #Injury #Diagnosis
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome • Diagnosis ... irrigation • Management ... Torsemide) • Acute ... , liver cirrhosis ... hyperaldosteronism • Acute
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