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HepatoRenal Syndrome - Pathophysiology

Dr. Edgar V. Lerma @edgarvlermamd - Nephrology Secrets https://amzn.to/34t5DgJ

#HRS #HepatoRenal #Syndrome #Pathophysiology #Diagnosis
HepatoRenal Syndrome ... - Pathophysiology ... amzn.to/34t5DgJ #HRS ... #Diagnosis #Nephrology ... #AKI
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... - Differential Diagnosis ... Distributive Shock, HRS ... Abdominal Compartment Syndrome ... #nephrology #causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... osmolarity If cause ... pressure • TTP / HUS ... • Cardio-renal syndrome ... #nephrology #causes
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
a.k.a. cardiorenal syndrome ... vasculitis - TTP/HUS ... tubular necrosis (causes ... Classification #diagnosis ... #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
- Differential Diagnosis ... • Hepatorenal syndromes ... Ethylene glycol) TTP/HUS ... #KidneyInjury #Nephrology ... #Algorithm #Causes
Hepatorenal Syndrome - Diagnosis and Management Summary
Who gets HRS?
 • Decompensated cirrhosis
 • Typically with existing
Hepatorenal Syndrome ... - Diagnosis and ... in HRS-AKI is vasoactive ... #HRS #Diagnosis ... #Management #treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... and Management ... Dermatomyositis) AKI ... - Pathophysiology ... #causes #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... fever - ACS, AKI ... #TLS #diagnosis ... #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Framework and Management ... Summary Causes ... #Management #causes ... #treatment #nephrology
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... hyperkalemia) BRASH Treatment ... • Aggressive treatment ... #diagnosis #management ... #pathophysiology