18 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... ANCA-positive vasculitis ... ANCA-negative vasculitis ... Investigations • Labs: CBC ... differential #diagnosis #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... and renal abnormalities ... Presentation - Systemic Symptoms ... Lab Tests: • CBC ... • Urinalysis (Renal
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Autoimmune ANCA vasculitis ... life-threatening diseases ... Inflammatory eye disease ... or serologies + symptoms
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- BMP, cap, CBC ... protein/Cr - Renal ... disease — 21% ... Glomerulonephritis or vasculitis ... AcuteKidneyInjury #AKI #Nephrology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
and renal abnormalities ... Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... cognitive impairment, neurologic
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... of active pulmonary ... decreased reflexes Pathophysiology ... for concomitant pulmonary ... intervention CMC
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
lesion Pott's Disease ... lymphadenopathy, pulmonary ... Meningitis • Include: vasculitis ... Children with pulmonary ... differential #TB #neurology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... interstitial lung disease ... /pulmonary fibrosis ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Pulmonary infarction ... 94 and 84% Renal ... : • Renal infarction ... tumor burden) Vasculitis ... associated with any symptoms
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Periodontal disease ... Lung Abscess Pathophysiology ... Diagnosis: • CBC ... Diagnosis: • Vasculitis ... Lung #Abscess #pulmonary