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CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Antimicrobial treatment ... status, and focal neurologic ... #differential # ... InfectiousDiseases #Neurology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Toxoplasmosis (CD4 ... splenomegaly Other infections ... multiple lesions Infectious ... Lesions #Brain #differential ... causes #radiology #neurology
IDSA Recommendations for Preventing and Treating Penicillium marneffei Infections in HIV-AIDS
Preventing 1st Episode of Penicilliosis (Primary
Penicillium marneffei Infections ... Treating Acute Infection ... IDSA #Prevention #Treatment ... opportunistic #infections ... #HIVAIDS #pharmacology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Perforation) Pathophysiology ... #1 nosocomial infection ... Treatment Guideline ... #Clostridium #Infection
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Artifact (redo CBC ... Myelofibrosis Infectious ... effect following treatment ... Thrombocytosis #Differential
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Triggering factor (infection ... →Activation of CD8 ... Unknown cause Treatment ... diagnosis #management #treatment
Migraine Treatment Overview

 • What is a Migraine?
 • Pathophysiology
 • Common Migraine Triggers
 • Diagnosis
Migraine Treatment ... • Pathophysiology ... Prophylactic Treatment ... #management #pharmacology ... #prophylaxis #neurology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... allopurinol), Infection ... Investigations • Labs: CBC ... DAH, rule out infection ... #diagnosis #nephrology
IDSA Recommendations for Treating Isospora belli Infection in HIV-AIDS
Treating Isospora belli Infection
General Management Considerations:
 • Fluid
Isospora belli Infection ... Patients with CD4 ... Sustained increase in CD4 ... IDSA #Prevention #Treatment ... #HIVAIDS #pharmacology
Cytomegalovirus (CMV) in HIV-AIDS Patients
Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family.
CMV infection: virus isolation or detection
CMV infection: virus ... patient with HIV and CD4 ... 50 or less: • Neurologic ... • Endocrine: Infectious ... AIDS #diagnosis #differential