14 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... APS), Secondary prevention ... CNS #neurology #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... Topical steroids • Prevention ... Neuro disease: • Systemic ... #pharmacology #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
incidentally via CBC ... Splenomegaly Treatment ... • Treatment is ... of symptoms and prevention ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
site in lymphatic system ... with lymphatic system ... Responsive to Treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
beta-spectrin, which is crucial ... vasculitis Treatment ... weeks #Scurvy #Pathophysiology ... #VitaminC #AscorbicAcid ... #Pathophysiology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... Lymphocytosis on CBC ... ’s CLL Scoring system ... microglobulin Treatment ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 • CMV end-organ disease is best
Infections in HIV-AIDS Preventing ... ART to maintain CD4 ... evident benefits of systemic ... therapy in preventing ... should include systemic
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... acute pulmonary, systemic ... Aspergillosis Pathophysiology ... the circulatory system ... Fluconazole SYSTEMIC
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
/aggregate) of CD4 ... Central nervous system ... Cytopenia: 2% Systemic ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology