7 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... : • Immune response ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... hypothyroid-induced myopathy, Guillain-Barré ... syndrome (GBS), ... , immune-mediated ... Statin Treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... fairly symmetric muscle ... the underlying pathophysiology ... and cauda equina TREATMENT ... #Barre #Syndrome
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
constipation Differential ... Tethered cord • Guillain-Barre ... lower extremity muscle ... axial T1 and T2 Treatment ... #differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Necrotizing, pauci-immune ... respiratory tracts Immune ... Joints: myalgia and muscle ... Lab Tests: • CBC ... #rheumatology #classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... erythematosus (SCLE ... permanent alopecia Differential ... context of primary immune ... titers > 1:80 • CBC
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... activation of the immune ... or triggers) is crucial ... Pathophysiology ... of NK cells and CD8