38 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... K), H. pylori test ... thyroid function test ... changes), high MCV anemia ... #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... leakage of RBC's secondary ... : ITP • Secondary ... - Hemolytic anemia ... #nonpalpable #dermatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
• Rheumatic disorders ... • Celiac disease ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Thrombocytopenia ... Sequestration Disordered ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Liver Function Tests ... renal failure/uremia ... Pruritus #primary #secondary ... #generalized #dermatology ... #causes
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Small Bowel Disorder ... Liver Function Tests ... Liver Function Tests ... #Causes #Hematology
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
hypotension - Nausea ... mild normocytic anemia ... Autoimmune thyroid disease ... : - Pale skin ... without marked anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Disease • Marrow ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #workup #hematology