93 results
IDSA Treatment Recommendations for Cryptococcal Meningoencephalitis - Induction, Consolidation and Maintenance Therapy

Table 2. Antifungal Treatment Recommendations
Recommendations for Cryptococcal ... Antifungal Treatment ... Recommendations for Cryptococcal ... Antifungal Treatment ... Antifungal Treatment
Spectrum of activity for systemic antifungal agents
Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
activity for systemic antifungal ... agents Antifungals ... Aspergillus fumigatus, Cryptococcus ... .2015.10.012 #Antifungal
Rare Invasive Yeasts - Species and Antifungal Therapy

Cryptococcus, 
Geotrichum, 
Kodamaea, 
(Pichia)ohmeri, 
Malassezia, 
Pseudozyma, 
Rhodotorula, 
Saccharomyces, 
Saprochaete
- Species and Antifungal ... Therapy Cryptococcus ... Invasive #Yeasts #Antifungal
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
Antifungal Polyenes ... : Zygomycetes, Cryptococcal ... Overview #Polyenes #Antifungal
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antifungal Echinocandins ... lack activity vs Cryptococcus ... Echinocandins #Antifungal
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
infections: Severe cryptococcal ... #Flutycosine #Antifungal
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
- Negative: Cryptococcus ... Paecilomyces, Cryptococcus ... of mold-active antifungals
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
cavitation • Cryptococcus ... patient has known cryptococcal ... for most OI • Cryptococcal ... -6 weeks after antifungal
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Cryptococcal meningitis ... Cryptococcal meningitis ... initiation of antifungal ... initiation of antifungal ... IUIDfellowship #Cryptococcal
Tinea Versicolor (Pityriasis versicolor) 
NOT a dermatophyte infection 
Caused by saprophytic, lipid-dependent yeasts 
Clinical 
 •
Management • Topical antifungals ... • Oral antifungal