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diagnosis differential infectiousdiseases infections fungal causes concurrent microbiology pulmonary betadglucan biomarkers cardiology endocarditis galactomannan hivaids management radiology table abscess aids
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
exceptions are Aspergillus ... polysaccharide capsule of Cryptococcus ... detection for cryptococcal ... mucopolysaccharide capsule of Cryptococcus ... fungi #fungus #comparison
Fungal Pneumonias - Diagnosis Comparison Table • Aspergillus • Blastomyces • Candida • Coccidioides • Cryptococcus
Pneumonias - Diagnosis Comparison ... Table • Aspergillus ... Coccidioides • Cryptococcus ... Pneumonias #Diagnosis #Comparison
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
negative culture Brain ... Mycobacteria - Fungal: Aspergillus ... , Cryptococcus, ... nocardia - Fungal: Cryptococcus ... Coccidiomycosis, Cryptococcus
Fungal Biomarkers: Comparing Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi •
Beta-D-Glucan and Aspergillus ... Spec ~77-96% Aspergillus ... constituent of Aspergillus ... Paecilomyces, Cryptococcus ... Galactomannan #diagnosis #comparison
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... Mucormycosis, Cryptococcus ... #Lung #Infections
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... Mucormycosis, Cryptococcus ... #Lung #Infections
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
lesions • 80% with lung ... histoplasmosis, cryptococcus ... , and aspergillus ... RingEnhancing #Lesions #Brain
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Beta-D-Glucan and Aspergillus ... - Negative: Cryptococcus ... Paecilomyces, Cryptococcus ... Clav (may be + as long ... Galactomannan #diagnosis #comparison
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
CD4 < 200: PCP, Aspergillus ... (Histoplasma, Cryptococcus ... failure, COPD, Lung ... ABG, BDG, Serum Cryptococcal
Radiographic appearances of pulmonary diseases in HIV/AIDS Patients • Diffuse Interstitial Infiltrates: Pneumocystis jirovecii, M.tuberculosis, Histoplasma
Coccidioides spp., Cryptococcus ... C.neoformans, Aspergillus ... Actinomyces spp., NHL; Lung ... C.neoformans, R.equi, Aspergillus
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