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diagnosis differential causes infectiousdiseases infections management cardiology comparison concurrent endocarditis fungal radiology aspergillus betadglucan biomarkers clinical cns crypto culture evaluation
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
• India ink - "Negative ... polysaccharide capsule of Cryptococcus ... detection for cryptococcal ... mucopolysaccharide capsule of Cryptococcus ... fungus #comparison #table
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Abscess - Differential ... culture Brain: ... : Aspergillus, Cryptococcus ... nocardia - Fungal: Cryptococcus ... Coccidiomycosis, Cryptococcus
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Lung abscess ... Lung Abscess - Clinical ... shows a small, stable ... Dermatitidis - Cryptococcus
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
lesions • 80% with lung ... histoplasmosis, cryptococcus ... Syphilis • Pyogenic Abscess ... RingEnhancing #Lesions #Brain
Differential Diagnosis for Concurrent Brain and Lung Infections • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
for Concurrent Brain ... and Lung Infections ... Mucormycosis, Cryptococcus ... @ID_fellows #Brain ... #Lung #Infections
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... Mucormycosis, Cryptococcus ... febrilepodcast #Brain ... #Lung #Infections
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... Mucormycosis, Cryptococcus ... febrilepodcast #Brain ... #Lung #Infections
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Coccidioides - Negative ... : Cryptococcus, ... Paecilomyces, Cryptococcus ... - Negative: ... Clav (may be + as long
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
Frequent false-negative ... valves • MRI brain ... common, Aortic root abscess ... often seen • MRI brain ... Marantic #diagnosis #table
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
verrucous) • Lung ... • Coagulase-negative ... Aspergillus • Cryptococcus ... annular or aortic abscess ... Complications: Abscess
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