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Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... 3) Number of Joints ... weight-bearing joints ... Number of Joints ... Inflammatory, crystalline
Gout: Pathogenesis and Clinical Findings - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders -
easily leaks into joints ... -> Uric acid crystallizes ... in a peripheral joint ... Neutrophils enter joint ... degradative enzymes into joint
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders ... • Septic • Crystalline ... Lumbar Spine and SI Joints ... @AmyChung #Joint
Synovial Fluid Analysis: Findings (COLOR TRANSPARENCY VISCOSITY WBC COUNT (PER MM3) PMN CELL COUNT (%) GRAM STAIN CULTURE PCR TEST CRYSTALS) By Condition (Normal Noninflammatory Inflammatory:
Inflammatory: crystalline ... Arthrocentesis #Joint
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 Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Cryoglobulinemic GN • Crystalline ... Scleromyxedema (CNS+GI+CVS+joints
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Pathogenesis and Joint ... poly-articular joint ... affecting the small joints ... Joint involvement ... space decr joint
Rheumatoid Arthritis - 2020 ACR-EULAR Classification ≥ 6 of 10 points = definite RA Joint Involvement:
= definite RA Joint ... 2-10 large joints ... , +/- large joints ... points >10 joints ... least 1 small joint
Common Forms of Arthritis in the Hands Acute Rheumatoid Arthritis Tender, painful, stiff joints in rheumatoid arthritis,
painful, stiff joints ... interphalangeal joints ... interphalangeal joints ... (Degenerative Joint ... Joint involvement
Phalanges - Hand Anatomy Joints between phalanges are named interphalangeal meaning “between phalanges.” Because each finger has
Hand Anatomy Joints ... interphalangeal joints ... interphalangeal) joint ... interphalangeal) joint
Reactive Arthritis • Inflammation of joints (commonly large joints) - Asymmetric Oligoarthritis: Joint
Inflammation of joints ... commonly large joints ... Oligoarthritis: Joint ... pain in a few joints ... ) - Large Joint
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