9 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
• Asplenia Laboratory ... High Glucose Content ... • Hemolytic anemia ... HbA1c #HgbA1c #Laboratory ... Increase #Decrease #Diagnosis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Tests - AST, ALT, Alkaline ... within liver Alkaline ... hepatocyte - Elevation ... Chemistry #Tests #Laboratory ... Pathophysiology #Diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• Pernicious anemia ... eliminated • Elevation ... phosphate &/or • Elevation ... Hyophosphatasia #hepatology ... #diagnosis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Areas of diagnostic ... magnitude of enzyme elevation ... and clinical context ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... ALT and AST - Elevations ... deficiency - Anemia ... leads to chronic anemia ... #Laboratory #Diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... result in severe anemia ... immune hemolytic anemia ... Mild-to-moderate elevation ... #Workup #Hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
appropriate clinical context ... - assess other laboratory ... Arterial Oxygen Content ... 30mmHg) - Severe anemia ... #typea #typeb #classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
and fever) and laboratory ... Skin Disease Classification ... Differential Diagnosis ... syndrome in the context ... lymphopenia, low PLT • Anemia
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Growers (Runyon Classification ... Growers (Runyon Classification ... Hematologic malignancy ... gastrointestinal symptoms (elevations ... Bone Marrow - Anemia