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hemeonc oncology syndrome apml chronic cll differentiation erythematosus hemophagocytic hlh leukemia leukostasis lupus lymphocytic lymphohistiocytosis lysis rheumatology sle systemic tls
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... cytopenias (ITP, AIHA ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... intracellular contents ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... opacities • Diagnosis ... : >3 symptoms, or ... #management #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... syndrome in the context ... : • AIHA 10% • ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Common Signs and Symptoms ... - Cytopenias (anemia ... Pathophysiology ... #Management #Hematology
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