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management rheumatology differential hemophagocytic lymphohistiocytosis oncology syndrome vasculitis accaha acidosis activation autoimmune behcet cardiology causes chf chronic classes clinical cll
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... Diagnosis via genetic ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Autoimmune diseases: SLE ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
causes in the context ... disease (10%) : SLE ... Vasculitis #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... erythematosus [SLE ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
heliotrope rash, Shaw sign ... , holster sign, ... Can also see mechanics ... after 2 years of treatment ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... organ damage • Treatment ... intracellular contents ... Syndrome #TLS #diagnosis ... #management #hematology
In order to better classify heart failure, the American College of Cardiology Foundation and the American
Below one can see ... With treatment, ... show symptoms or signs ... patients with a diagnosis ... #Diagnosis #Cardiology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
haploidentical>unrelated>HLA ... Conditioning regimen Signs ... symptoms, unexplained hematologic ... EBV viral load, signs ... and classification
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... #classification ... #hematology #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment ... #management #signs
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