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diagnosis differential management dermatology disease erythematosus lupus oncology peds sle vasculitis signs symptoms algorithm ana antinuclear treatment antibodies autoantibodies causes
Staphylococcal Scalded Skin Syndrome (SSSS) (aka Ritter disease) #Staphylococcal #Scalded #Skin #Syndrome #SSSS #Diagnosis #Pediatrics #Dermatology #Ritter
Staphylococcal Scalded Skin ... Syndrome (SSSS) ... #Syndrome #SSSS ... #Diagnosis #Pediatrics ... #Dermatology #Ritter
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... Scleroderma) Multi-system ... LcSSc) - distal skin ... changes): skin ... Scleroderma #SSc #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... anti-Sc170): Diffuse skin ... Rapid progressive skin ... BCM_InternalMed #Systemic ... Autoantibodies #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... joints Nervous system ... Demyelinating syndromes ... symptoms #diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
• Homogeneous: Systemic ... ) • Speckled: Systemic ... SLE), Sjogren's Syndrome ... • Peripheral: Systemic ... ANA #patterns #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... refractory disease Skin ... Neuro disease: • Systemic ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #joint #pain #skin ... differential #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... hypersensitivity syndromes ... Diagnosis #Management #Hematology ... #Rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Causes == Primary Skin ... • Xerosis (dry skin ... Lesion / Systemic ... Myelodisplastic syndrome ... #generalized #dermatology
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