10 results
Lactic Acidosis Classification - Type A vs Type B
Type A Lactic Acidosis: Sepsis, Ischemic bowel, Hemorrhagic
Lactic Acidosis ... Liver Disease, Malignancy ... Short bowel (D-lactate ... #TypeB #diagnosis ... #differential #
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
Diagnosis Type ... Carbon monoxide, Cyanide ... inborn errors of metabolism ... #Diagnosis #TypeA ... #TypeB #lactate
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... impairment of cellular metabolism ... sweat) - its metabolism ... drugs, seizures, malignancy ... - Cocaine - Cyanide
Anion Gap Metabolic Acidosis
 • Diabetic Ketoacidosis ± Hyperglycemia ± Hyperosmolar
 • Alcoholic Ketoacidosis ± Hyperglycemia
Anion Gap Metabolic ... Ethylene glycol • Type ... Deficiency - Malignancy ... #Acidosis #differential ... #diagnosis
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Framework Type ... Inborn Errors of Metabolism ... Late Sepsis), Malignancy ... #Differential #
Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis
	• DKA
		- With normal glucose, ask if
Metabolic Acidosis ... • Type A = tissue ... • Type B = lymphoma ... #Acidosis #diagnosis ... #differential
Type B Lactic Acidosis
Elevated lactic acid when no systemic hypoperfusion is apparent
Causes:
 • Drugs (metformin, linezolid,
Type B Lactic Acidosis ... to clear) • D-lactate ... inborn errors of metabolism ... #causes #differential ... #diagnosis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
The presence of metabolic ... obstruction due to malignancy ... normalised ratio; LDH, lactate ... disease; T2DM, type ... Liver #Enzymes #Differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Heat stroke - Metabolic ... Dermatomyositis Clinical ... Isotonic fluid/Lactated
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Disease 3 Types ... disorder or lymphoid malignancy ... Viral Infection Clinical ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential