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diagnosis anemia cold differential agglutinin causes cryofibrinogenemia disease extravascular hemolysis intravascular rheumatology testing warm workup
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Immunosuppression, Splenectomy Cold ... Autoimmune Hemolytic ... BostonChiefs #Warm #Cold ... #Anemia #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... Warm AIHA • Cold ... AIHA • Alloimmune ... Complement-Mediated • Cold ... #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Viral infection, autoimmune ... CLL (older) • Autoimmune ... sensitize red blood cells ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... • Sickle cells ... Agglutination - Cold ... elliptocytosis, autoimmune ... #workup #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogen is a cold ... - Albumin - Cold ... associated with autoimmune ... may include: • Cold ... thrombophlebitis, pulmonary
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