10 results
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... result in permanent neurologic ... deficiency - Syrinx ... Lower motor neuron symptoms ... Upper motor neuron symptoms
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... Agglutinin Syndrome ... sensitize red blood cells ... hemolytic #anemia #hematology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... Framework Spinal cord ... level of spinal cord ... of the spinal cord ... MCTD, Sjogren syndrome
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... Reconstitution Inflammatory Syndrome ... lymphadenopathy, pulmonary ... Children with pulmonary
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
: inheriting 2 copies ... Loss of parental copy ... Signs/Symptoms ... , sleep apnea, cor ... pulmonale #PraderWilli
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogen is a cold ... - Albumin - Cold ... Cryofibrinogenemia Symptoms ... may include: • Cold ... #hematology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... ‘red flag’ symptoms ... Diagnosis: • Spinal cord ... spondylitis • Tethered cord ... diagnosis #causes #neurology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... of breath • Neurologic ... neutrophil count < 500 cells ... Epidural Spinal Cord
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... matter, spinal cord ... meningitis), MCC CNS symptoms ... management #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Multinucleated giant cells ... affects the skin, neurologic ... • Progressive symptoms ... cognitive impairment, neurologic