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differential management syndrome hematology signs spinalcord syndromes acute als amyotrophic anorexianervosa apml cancer cauda caudaequina causes complications cryofibrinogenemia differentiation emergencies
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... findings • Anterior Cord ... complete • Central Cord ... Syndrome ->Cord ... • Posterior Cord
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... deficiency - Syrinx ... Lower motor neuron symptoms ... #differential #diagnosis ... #neurology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... of breath • Neurologic ... neutrophil count < 500 cells ... Epidural Spinal Cord ... #differential #diagnosis
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... lymphadenopathy, pulmonary ... Children with pulmonary ... #Tuberculosis #diagnosis
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Loss of parental copy ... Syndrome Signs/Symptoms ... , sleep apnea, cor ... pulmonale #PraderWilli ... Syndrome #genetics #pathophysiology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
of the spinal cord ... monophasic Pathophysiology ... to the spinal cord ... Bilateral signs and/or symptoms ... #management #neurology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... ‘red flag’ symptoms ... : • Spinal cord ... spondylitis • Tethered cord ... #causes #neurology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogen is a cold ... - Albumin - Cold ... Cryofibrinogenemia Symptoms ... may include: • Cold ... thrombophlebitis, pulmonary
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Release from blast cells ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... management #hematology #oncology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Microglial cells ... multiple spinal cord ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology
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