22 results
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... result in permanent neurologic ... syphilis, and HIV ... #differential # ... diagnosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... Framework Spinal cord ... level of spinal cord ... , HIV, CMV, HTLV ... MCTD, Sjogren syndrome
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin ... Agglutinin Syndrome ... Mycoplasma, EBV, HIV ... younger pts) Differential ... sensitize red blood cells
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... Tuberculosis #diagnosis #differential
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
‘red flag’ symptoms ... Diagnosis: • Spinal cord ... infarct • HIV ... spondylitis • Tethered cord ... diagnosis #causes #neurology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
: inheriting 2 copies ... Loss of parental copy ... Signs/Symptoms ... , sleep apnea, cor ... pulmonale #PraderWilli
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
of the spinal cord ... Bilateral signs and/or symptoms ... simplex virus, HIV ... diagnosis #management #neurology ... #differential
Hypoxemic Respiratory Failure - Differential Diagnosis Framework
DECREASED INSPIRED OXYGEN
 • Low PATM Can decrease first part
Respiratory Failure - Differential ... respiratory drive due to neurologic ... obesity-hypoventilation syndrome ... Pneumonia, asthma, COPD ... hepatopulmonary syndrome
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... obstruction • COPD ... Physical stigmata of cor ... , CCP, ANCA • HIV ... #differential #
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... disorder (Cardiac, pulmonary ... of the spinal cord ... parainfluenza, Coxsackie, HIV ... #Diagnosis #neurology