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diagnosis differential hematology management disorders rheumatology spinal spinalcord abg acid acidbase agglutinin algorithm als amyotrophic anemia base bloodgas bronchiectasis cauda
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... result in permanent neurologic ... syphilis, and HIV ... deficiency - Syrinx ... Lower motor neuron symptoms
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... Framework Spinal cord ... level of spinal cord ... , HIV, CMV, HTLV ... MCTD, Sjogren syndrome
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... Agglutinin Syndrome ... Mycoplasma, EBV, HIV ... sensitize red blood cells
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... lymphadenopathy, pulmonary
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
‘red flag’ symptoms ... Diagnosis: • Spinal cord ... infarct • HIV ... spondylitis • Tethered cord ... diagnosis #causes #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
of the spinal cord ... to the spinal cord ... Bilateral signs and/or symptoms ... simplex virus, HIV ... diagnosis #management #neurology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Progressive MS (Spinal cord ... objective evidence of neurologic ... • Acute: - IV ... diagnosis #management #neurology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
: inheriting 2 copies ... Loss of parental copy ... Signs/Symptoms ... , sleep apnea, cor ... pulmonale #PraderWilli
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... obstruction • COPD ... • Mounier-Kuhn syndrome ... Physical stigmata of cor ... , CCP, ANCA • HIV
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Amyotrophic Lateral Sclerosis ... multiple spinal cord ... fasciculations Common Symptoms ... motor neurons - IV ... #neurology #diagnosis
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