227 results
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
alter inflammatory cytokine ... GCA is almost never ... /Symptoms: - Fever
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... Fever: • Regulated ... Endotoxins, Toxins, Cytokines ... production • Treatment ... BrighamChiefs #Fever
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
pro-inflammatory cytokines ... hemophagocytosis and cytokine ... disease • Periodic fever ... - Nonremitting fever ... Treatment: • Corticosteroids
Rodent-associated Bacterial infections: Leptospirosis, Rat-bite fever, Tularemia, Plague 

#rodent
#infections
#leptospirosis
#tularemia
#ratbitefever
#plague
#rats
#infectiousdisease
#fever
#differential
#diagnosis
#management
#treatment
#table
Leptospirosis, Rat-bite fever ... infectiousdisease #fever ... #management #treatment
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
Pathogenesis of Rheumatic Fever ... Pathogenesis of rheumatic fever ... infiltration leading to cytokine-mediated ... #Rheumatic #Fever
Dengue Fever - Diagnosis and Management Summary 
Dengue Fever → Dengue Hemorrhagic Fever →Dengue Hemorrhagic Shock
Dengue Fever - Diagnosis ... Summary Dengue Fever ... Dengue Hemorrhagic Fever ... Presentation: Fever ... 7 days (Ig)M Treatment
UTI treatment
#Diagnosis #UrinaryTract #Infection #UTI #Definition #Uncomplicated  #UrinaryTract #Infection #UTI #Algorithm #Diagnosis #Management #Urinary #Tract
UTI treatment # ... #UrinaryTract #Fever
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology: • Cytokine ... Subacute-Acute: • Common: fever ... Renal Failure Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
activation and cytokine ... following: • Fever ... • Bicytopenia Treatment ... diagnosis #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
pro-inflammatory cytokines ... • Clinical: fever ... Unknown cause Treatment ... diagnosis #management #treatment