17 results
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
Diagnosis was made ... testing and expedite treatment ... with clinical trials ... neurotoxic • Symptoms ... • Symmetric abnormal
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
shunt (Type 2) Clinical ... blood gas (ABC) ... ) on room air Treatment ... resolution of symptoms ... #management #treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... fraction < 20% Differential ... Diaqnoses: • ... #management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
treatment Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... Renal Failure Treatment ... 500 mg QD until normal
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Hyperthyroidism Overview Clinical ... ↑ AST/ALT • Treatment ... Ophthalmoplegia • Atrial ... #differential # ... endocrinology #signs #symptoms
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
Digoxin toxicity Symptoms ... (≥ 0.12s) with abnormal ... Diagnosis: • PAC ... more intensive treatment ... #differential #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Dermatomyositis Clinical ... Features: • Triad ... of symptoms:
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Highly variable clinical ... - Symptoms of ... upper limit of normal ... Anti-LKM & Anti-ALC ... regarding need for treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... meningitis), MCC CNS symptoms ... Behcet syndrome (Clinical ... Behcet disease) Differential ... Arthritis, AS Treatment
Dysphagia - Differential Diagnosis Framework

Symptom | Diagnosis
• Solid-food dysphagia present for months to years | Mechanical
Dysphagia - Differential ... Symptom | Diagnosis ... Mediastinal mass, Left atrial ... disorder → EGD Treatment ... #gastroenterology