405 results
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
P-Glycoprotein - Key DDI
Paxlovid Drug-Drug Interactions
Before prescribing ritonavir-boosted nirmatrelvir (Paxlovid) for outpatient treatment of COVID-19, determine whether the patient
#Interactions #DDI
Cannon A Waves on Neck Examination

Cannon a waves! Notice that it occurs randomly, not predictably w/
dual-chamber PPM set for DDI
â–º
Central vs Nephrogenic Diabetes Insipidus - Desmopressin Challenge
Give desmopressin (intranasal, SQ, IV) and monitor UOsm every
300 - Complete NDI ... 300 - Partial NDI ... 300 - Partial CDI ... 100% - Complete CDI ... Diabetes #Insipidus #DI
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
#pharmacology #DDI
Statin Drug-Drug Interactions with HIV ART Medications
PIs - NNRTIs - ISTIs
Dose Adjustments

doi: 10.20945/2359-3997000000306

#Statin #Drug #Interactions #DDIs
Dose Adjustments doi ... #Interactions #DDIs
Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients

CJASN May 2019, 14 (5)
14 (5) 656-663; DOI ... Conclusions We did
DSI Checklist

#Management #CriticalCare #Airway #DelayedSequence #DSI #Intubation #Checklist #HEAVEN #Mnemonic
DSI Checklist ... DelayedSequence #DSI
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
//www.nejm.org/doi ... spironolactone did
POLAR Randomized Clinical Trial - Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients
21):2211-2220. doi ... with normothermia did