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diagnosis oncology rheumatology mds anemia aplastic cardiology classification common cryofibrinogenemia cryoglobulinemia cryoglobulins cvid dermatology differential endocarditis hypogammaglobulinemia immunodeficiency immunology infectiousdiseases
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... old, ~10,000 new cases ... risk-stratification • Risks: infection ... #treatment #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... petechiae) • Frequent infections ... Macrocytic anemia DDX ... • Parvovirus infection ... #hematology #oncology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... : HCV infection, ... DDX: • ANCA (Antineutrophil ... classification #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... and thymoma DDX ... • Hypocellular myelodysplastic ... Anemia #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... gastrointestinal infection ... DDX: - Pyoderma ... Leukocytoclastic vasculitis
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... Malignancy • Infections ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Hypercoagulable (APLAS) Microbiology ... Glomerulonephritis DDX ... valvular disease • Vasculitis ... Cholesterol emboli syndrome ... Septic emboli cause
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
40 years old DDX ... ANCA-associated vasculitis ... - Infectious disorders ... TAFRO #diagnosis #management ... #rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
dysfunction DDX ... Behcet disease • Infections ... Bacterial ○ Viral infection ... Polychondritis #rheumatology ... #diagnosis #management
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