2335 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus (DIL ... rash is rare in DIL ... , SCLE-DIL (terbinafine ... for cutaneous DIL ... for cutaneous-DIL
Thrombotic Thrombocytopenic Purpura (TTP) vs Disseminated Intravascular Coagulation (DIC)
#Diagnosis #TTP #DIC #Comparison #Table #Laboratory #Findings #RebelEM
Intravascular Coagulation (DIC ... Diagnosis #TTP #DIC
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation (DIC ... Manifestations of DIC ... MAHA: TTP/HUS > DIC ... increase > 100mg/dL ... for bleeding #DIC
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... Pharmacology #Causes #DILI
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Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Bilirubin: <5 mg/dL ... Bilirubin: <5 mg/dL ... DIC • Aminotransferases ... Bilirubin: often <5 mg/dL
Mallet Finger
Absence of a fracture does NOT exclude Mallet finger, the extension function of the DIP
function of the DIP ... distal to the DIP ... Swollen and tender DIP ... Extension splint of DIP
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... ) DILI Types: ... disease 6-9 mo after DILI ... • Cholestatic DILI ... EmoryGastroHep #DILI
After emergency intubation, 33% percent of older adults die during the index hospitalization. #EBM #PatientInfo #Geriatrics
of older adults die
Muehrcke's Lines (Leukonychia striata)
Narrow while transverse lines (Not depressed, compared to Beau's lines). Usually 2 or
less than < 2.2 g/dL ... #Fingernails #PhysicalExam
Thrombocytopenia 
Work up, differential diagnosis and management.

Satyendra Dhar MD, @DharSaty

#thrombocytopenia #platelets #ITP #DIC
platelets #ITP #DIC