405 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... ) DILI Types: ... • Cholestatic DILI ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Liver Injury (DILI ... Cirrhosis #Hepatology #gastroenterology
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... Pharmacology #Causes #DILI
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Liver Injury (DILI ... Diagnosis Algorithm DILI ... injury, Previous DILI ... hepatitis #DILI
Drug-Induced Liver Injury - Pathophysiology
Indirect
Idiosyncratic
Direct

BWH Medicine Chiefs @BrighamChiefs

#DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
BrighamChiefs #DILI
HFNC compared to NIV
HFNC:
- Comfort - Higher comfort  Eating, drinking and speaking less impaired 
-
preload - P-SILI ... /VILI - Lower risk
Amiodarone-Induced Lung Iniurv (AILI) - Timeline
Hours to days (peri-procedurally): ARDS
Days to months: DAH
Weeks: Eosinophilic pneumonia
Weeks to
Amiodarone-Induced Lung Iniurv (AILI ... Induced #LungIniurv #AILI
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
• Iatrogenic: DILI
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
GTT, indirect bili ... Referral #Hepatology #Gastroenterology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
(>1000): • DILI