312 results
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
hypereosinophilia (HE) Caused ... cytokines Common causes ... disease Rare causes ... CD3-CD4+ T cells ... Differential #Diagnosis #Causes
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... deficit: - Type I DM ... produced - Type II DM ... #dka #hhs #pathophysiology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
74% of anti-MDA5 DM ... lesser extent, DM ... Dermatomyositis • Anti-MDA5 DM ... Women • ~20% of cases ... Men • ~50% of cases
Jaundice - Pathophysiology and Causes

- Amy Chung, MD, MSc @AmyChung 

#Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... and Causes - ... #Jaundice #Pathophysiology ... #Unconjugated #Causes
Causes and Pathophysiology of Hypertension

#Causes #Pathophysiology #Hypertension #Primary #Essential #Secondary #Differential

** GrepMed Recommended Text: Guyton and
Causes and Pathophysiology ... Hypertension #Causes ... #Pathophysiology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis (DM ... regeneration, diffuse CD8 ... Dermatomyositis #DM ... PM #Diagnosis #Pathophysiology
Congestive Heart Failure - Causes, Pathophysiology and Differential Diagnosis
 • Dilated Cardiomyopathy 
 • Hypertrophic Cardiomyopathy
Heart Failure - Causes ... , Pathophysiology ... • Other HFpEF Causes ... #HeartFailure #Causes ... #Pathophysiology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Secondary Causes ... 90 (>130/80 for DM ... end-organ damage or DM ... withdrawal Anatomic Causes ... RAS Metabolic Causes
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Shock #Shock #Pathophysiology ... diagnosis #algorithm #causes
The Pathophysiology of Fat Absorption and Causes of Malabsorption (steatorrhoea)

#Fat #Malabsorption #Pathophysiology #Differential #Steatorrhea #Diarrhea #Diagnosis
The Pathophysiology ... Absorption and Causes ... Malabsorption #Pathophysiology